TGF-beta/Smad
VEGFR
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Product name : Belizatinib (TSR-011, TSR011, TSR 011)
Product No. : 201712253958
Price : 100mg/$675; 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
Belizatinib (CAS: 1357920-84-3) is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase. The inhibition leads to disruption of ALK- and TRK-mediated signaling and impedes tumor cell growth in ALK/TRK-overexpressing tumor cells.
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